4-Benzyl-1-(2-benzyloxycarbonylamino-ethyl)-piperidine-4-carboxylic acid ethyl ester → 1-(2-Amino-ethyl)-4-benzyl-piperidine-4-carboxylic acid ethyl ester

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Reaction Steps

4-Benzyl-1-(2-benzyloxycarbonylamino-ethyl)-piperidine-4-carboxylic acid ethyl ester (4.25 g, 10 mmol) is dissolved in MeOH (100 mL) and Pd—C (10%, 0.5 g) is added. The mixture is hydrogenated (7 bar, 20° C.) for 2 h. The catalyst is filtered off and the solvent evaporated to provide the title compound.

Provenance & Evidence