HCID 17956507, compound → HCID 59715934, compound

HRID 2223740Notes

Reaction equation

HRID 2223740 reaction equation
[NH2:1][CH2:2][CH2:3][N:4]1[CH2:9][CH2:8][C:7]([CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)([OH:10])[CH2:6][CH2:5]1.[CH2:18]([N:25]([CH3:35])[C:26]1[CH:31]=[C:30]([N:32]=[C:33]=[O:34])[CH:29]=[CH:28][N:27]=1)[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>>[CH2:11]([C:7]1([OH:10])[CH2:8][CH2:9][N:4]([CH2:3][CH2:2][NH:1][C:33]([NH:32][C:30]2[CH:29]=[CH:28][N:27]=[C:26]([N:25]([CH2:18][C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[CH3:35])[CH:31]=2)=[O:34])[CH2:5][CH2:6]1)[C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1

Participants

3

Reactant 2

HCID 17956507HCID 17956507, compoundHCID 22643335HCID 22643335, compound

Product 1

HCID 59715934HCID 59715934, compound

Procedure

The compound is prepared from 1-(2-amino-ethyl)-4-benzyl-piperidin-4-ol (93 mg, 0.40 mmol) and 2-(benzyl-methyl-amino)-4-isocyanato-pyridine (95.7 mg, 0.40 mmol) using the method described for Example 388D.

Sources & evidence

ORD record
ord-161af952d41c4816bbe864e52ec55320
Source dataset
uspto-grants-2008_05
Patent number
US07375227B2

Reaction notes

Loading…