Potassium Carbonate → HCID 59715052, compound

Participants

Reaction Steps

To a solution of 2-(acetoxymethyl)-2-[2-[1-[2-[4-[N-(p-tolyl)-2-furancarboxamido]piperidin-1-yl]ethyl]cyclohexyl]ethyl]-1,4-diacetoxybutane (synthesized in Example 14) (313 mg) dissolved in methanol (5 mL) was added potassium carbonate (39 mg) at room temperature. The solution was stirred for 20 hours. The reaction solution was concentrated under reduced pressure. Water was added to the resulting residue and extracted with a mixed solvent of chloroform-ethanol (80:20). The organic layer was dried over anhydrous magnesium sulfate, filtered and then concentrated under reduced pressure to give the title compound (252 mg).

Provenance & Evidence