HCID 69144794, compound → HCID 178426572, compound

Participants

Reaction Steps

N-[1-[2-[1-[2-(1,2-Di-tert-butoxycarbonylguanidino)ethyl]cyclohexyl]ethyl]piperidin-4-yl]-N-(5-methylpyridin-2-yl)-2-furancarboxamide (synthesized in Example 44) (105 mg) was dissolved in a 4N hydrochloric acid/1,4-dioxane solution (12 mL) and methanol (5 mL). The solution was stirred at room temperature for 2 days. The solvent was distilled off under reduced pressure and the resulting residue was crystallized (from methanol-ethyl acetate) to give the title compound (69 mg).

Provenance & Evidence