Hydrochloric Acid → HCID 58641526, compound

Participants

Reaction Steps

2-[(7-Benzenesulfonyl-2,3-dihydro-benzo[1,4]oxazine-4-carbonyl)-amino]-ethyl}-carbamic acid tert-butyl ester (38 mg) was dissolved in 1 mL ethanol and combined with 1 mL of 2N ethanolic HCl and refluxed for 30 minutes. Upon cooling, a white crystalline solid precipitated and filtration gave 25 mg. of 7-benzenesulfonyl-2,3-dihydro-benzo[1,4]oxazine-4-carboxylic acid (2-amino-ethyl)-amide hydrochloride. MS: 362 (M+H)+, mp: 220.9-221.3° C.

Provenance & Evidence