HCID 11710183, compound → HCID 11515992, compound

HRID 2224080Notes

Reaction equation

HRID 2224080 reaction equation
C(OC([N:8]1[CH2:13][CH2:12][CH:11]([NH:14][C:15]2[CH:20]=[C:19](S(C3C=CC=CC=3)(=O)=O)[CH:18]=[CH:17][C:16]=2[O:30][CH2:31][CH2:32]Br)[CH2:10][CH2:9]1)=O)(C)(C)C.[C:34]1([S:40](C2C=CC3OCCN(C4CCNCC4)C=3C=2)(=[O:42])=[O:41])[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1>>[C:34]1([S:40]([C:18]2[CH:19]=[CH:20][C:15]3[N:14]([CH:11]4[CH2:10][CH2:9][NH:8][CH2:13][CH2:12]4)[CH2:32][CH2:31][O:30][C:16]=3[CH:17]=2)(=[O:42])=[O:41])[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1

Participants

3

Reactant 2

HCID 11710183HCID 11710183, compoundHCID 68434968HCID 68434968, compound

Product 1

HCID 11515992HCID 11515992, compound

Procedure

Similarly prepared using 4-[5-benzenesulfonyl-2-(2-bromo-ethoxy)-phenylamino]-piperidine-1-carboxylic acid tert-butyl ester, was 6-Benzenesulfonyl-4-piperidin-4-yl-3,4-dihydro-2H-benzo[1,4]oxazine, MS: 359 (M+H)+, mp: 147.0-149.8° C.

Workup

  1. customSimilarly prepared

Sources & evidence

ORD record
ord-951e08645d5242558c5cc6971bc480b2
Source dataset
uspto-grants-2008_05
Patent number
US07378415B2

Reaction notes

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