HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine → 6-Acetyl-8-chloro-3-fluoro-5,6-dihydro-2-(6-methoxy-3-pyridinyl) pyrido[3,2-c][1]benzazocine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine | HCID 16217714 | — |
| Reactant | 6-Acetyl-3-fluoro-5,6-dihydro-2-(6-methoxy-3-pyridinyl)-pyrido[3,2-c][1]benzazocine | HCID 69291197 | — |
| Reactant | 6-Acetyl-2,8-dichloro-3-fluoro-5,6-dihydropyrido[3,2-c][1]benzazocine | HCID 85424790 | — |
| Product | 6-Acetyl-8-chloro-3-fluoro-5,6-dihydro-2-(6-methoxy-3-pyridinyl) pyrido[3,2-c][1]benzazocine | HCID 69292221 | — |
Reaction Steps
The title compound was prepared from 6D and 2A by a route analogous to that used for the preparation of 2B. HPLC Rt=3.412 min; LCMS Found: (M+H)+=410.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07378426B2 |
| Source dataset | uspto-grants-2008_05 |
| ORD ID | ord-05ff35de7d464b47b2db3fddf50b13e1 |
| Source note | uspto-grants-2008_05 |