HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Bromo-2-(bromomethyl)-6-chloropyridine → 1-(2-chloro-12H-1,11-diaza-dibenzo[a,e]cycloocten-11-yl)-ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Bromo-2-(bromomethyl)-6-chloropyridine | HCID 23249915 | — |
| Reactant | 6-Acetyl-2-chloro-3-fluoro-5,6-dihydro-pyrido[3,2-c][1]benzazocine | HCID 74393412 | — |
| Product | 1-(2-chloro-12H-1,11-diaza-dibenzo[a,e]cycloocten-11-yl)-ethanone | HCID 72366779 | 28% |
Reaction Steps
Compound 55C (27.7 mg, 28%) was prepared from bb (56.4 mg, 0.35 mmol) and 55B (100 mg, 0.35 mmol) in two steps by a route analogous to that used for the preparation of 1D.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07378426B2 |
| Source dataset | uspto-grants-2008_05 |
| ORD ID | ord-00c9b9de4e3646a6b2ad599a00143c30 |
| Source note | uspto-grants-2008_05 |