(2-Nitrophenyl)boronic acid → (2-Aminophenyl)boronic acid

Participants

Reaction Steps

A mixture of 84A (1.0 g, 6 mmol) and 10% Pd/C (50 mg) in EtOH (50 mL) was hydrogenated in a Paar shaker at 1 bar for 8 hours. The mixture was filtered through a pad of celite and the filtrate was concentrated. The resulting residue was triturated with hexanes and the resulting solid was filtered to afford 84B (0.4g, 50%).

Provenance & Evidence