HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Morpholine-4-sulfonyl)aniline → 5-(4-Methoxy-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid[3-(morpholine-4-sulfonyl)-phenyl]-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Morpholine-4-sulfonyl)aniline | HCID 559410 | — |
| Reactant | 5-(4-Methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid | HCID 781432 | — |
| Product | 5-(4-Methoxy-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid[3-(morpholine-4-sulfonyl)-phenyl]-amide | HCID 69291896 | — |
Reaction Steps
The title compound was prepared from 5-(4-methoxy-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid [CAS 333761-72-1; commercially available] and 3-(morpholine-4-sulfonyl)-phenylamine [CAS 22184-97-0; commercially available] according to general procedure II. Yellow solid. MS (ISP) 562.4 [(M+H)+]; mp 203° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07378417B2 |
| Source dataset | uspto-grants-2008_05 |
| ORD ID | ord-e2da2fae79cf4fe99e0e852125e0a5c2 |
| Source note | uspto-grants-2008_05 |