HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Morpholine-4-sulfonyl)aniline → 5-(4-Chloro-phenyl)-7-difluoromethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid[3-(morpholine-4-sulfonyl)-phenyl]-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Morpholine-4-sulfonyl)aniline | HCID 559410 | — |
| Reactant | 5-(4-Chloro-phenyl)-7-difluoromethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid | HCID 66650326 | — |
| Product | 5-(4-Chloro-phenyl)-7-difluoromethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid[3-(morpholine-4-sulfonyl)-phenyl]-amide | HCID 69292342 | — |
Reaction Steps
The title compound was prepared from 5-(4-chloro-phenyl)-7-difluoromethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (example C.3) and 3-(morpholine-4-sulfonyl)-phenylamine [CAS 22184-97-0; commercially available] according to general procedure II. Yellow solid. MS (ISP) 548.3 [(M+H)+]; mp 253° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07378417B2 |
| Source dataset | uspto-grants-2008_05 |
| ORD ID | ord-e381df2e9e024acab68206a255f96239 |
| Source note | uspto-grants-2008_05 |