3-(4-Methylpiperazine-1-sulfonyl)aniline → HCID 69291919, compound

HRID 2224422Notes

Reaction equation

HRID 2224422 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:9]2[CH:14]=[C:13]([CH:15]([F:17])[F:16])[N:12]3[N:18]=[CH:19][C:20]([C:21](O)=[O:22])=[C:11]3[N:10]=2)[CH:5]=[CH:6][C:7]=1[Cl:8].[CH3:24][N:25]1[CH2:30][CH2:29][N:28]([S:31]([C:34]2[CH:35]=[C:36]([NH2:40])[CH:37]=[CH:38][CH:39]=2)(=[O:33])=[O:32])[CH2:27][CH2:26]1>>[CH3:24][N:25]1[CH2:30][CH2:29][N:28]([S:31]([C:34]2[CH:35]=[C:36]([NH:40][C:21]([C:20]3[CH:19]=[N:18][N:12]4[C:13]([CH:15]([F:16])[F:17])=[CH:14][C:9]([C:4]5[CH:5]=[CH:6][C:7]([Cl:8])=[C:2]([Cl:1])[CH:3]=5)=[N:10][C:11]=34)=[O:22])[CH:37]=[CH:38][CH:39]=2)(=[O:33])=[O:32])[CH2:27][CH2:26]1

Participants

3

Reactant 2

HCID 31976483-(4-Methylpiperazine-1-sulfonyl)anilineHCID 4768478HCID 4768478, compound

Product 1

HCID 69291919HCID 69291919, compound

Procedure

The title compound was prepared from 5-(3,4-dichloro-phenyl)-7-difluoromethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (example C.7) and 3-(4-methyl-piperazine-1-sulfonyl)-phenylamine [CAS 436095-35-1] according to general procedure II. Yellow solid. MS (ISP) 595.3 [(M+H)+]; mp 229° C.

Sources & evidence

ORD record
ord-c73ddb78772c4a9081b3cebfdfd1724d
Source dataset
uspto-grants-2008_05
Patent number
US07378417B2

Reaction notes

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