3-(4-Methylpiperazine-1-sulfonyl)aniline → HCID 69293563, compound

HRID 2224423Notes

Reaction equation

HRID 2224423 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:9]2[CH:14]=[C:13]([C:15]([F:18])([F:17])[F:16])[N:12]3[N:19]=[CH:20][C:21]([C:22]([OH:24])=O)=[C:11]3[N:10]=2)[CH:5]=[CH:6][C:7]=1[Cl:8].[CH3:25][N:26]1[CH2:31][CH2:30][N:29]([S:32]([C:35]2[CH:36]=[C:37]([NH2:41])[CH:38]=[CH:39][CH:40]=2)(=[O:34])=[O:33])[CH2:28][CH2:27]1>>[CH3:25][N:26]1[CH2:31][CH2:30][N:29]([S:32]([C:35]2[CH:36]=[C:37]([NH:41][C:22]([C:21]3[CH:20]=[N:19][N:12]4[C:13]([C:15]([F:17])([F:18])[F:16])=[CH:14][C:9]([C:4]5[CH:5]=[CH:6][C:7]([Cl:8])=[C:2]([Cl:1])[CH:3]=5)=[N:10][C:11]=34)=[O:24])[CH:38]=[CH:39][CH:40]=2)(=[O:34])=[O:33])[CH2:28][CH2:27]1

Participants

3

Reactant 2

HCID 31976483-(4-Methylpiperazine-1-sulfonyl)anilineHCID 666502945-(3,4-Dichloro-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid

Product 1

HCID 69293563HCID 69293563, compound

Procedure

The title compound was prepared from 5-(3,4-dichloro-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (example C.9) and 3-(4-methyl-piperazine-1-sulfonyl)-phenylamine [CAS 436095-35-1] according to general procedure II. Yellow solid. MS (ISP) 613.3 [(M+H)+]; mp 181° C.

Sources & evidence

ORD record
ord-1092eeb82b3c4a008372adba42602c5c
Source dataset
uspto-grants-2008_05
Patent number
US07378417B2

Reaction notes

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