3-(4-Methylpiperazine-1-sulfonyl)aniline → HCID 87769137, compound

HRID 2224427Notes

Reaction equation

HRID 2224427 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([C:12]2[CH:17]=[C:16]([C:18]([F:21])([F:20])[F:19])[N:15]3[N:22]=[CH:23][C:24]([C:25](O)=[O:26])=[C:14]3[N:13]=2)[CH:5]=[CH:6][C:7]=1[C:8]([F:11])([F:10])[F:9].[CH3:28][N:29]1[CH2:34][CH2:33][N:32]([S:35]([C:38]2[CH:39]=[C:40]([NH2:44])[CH:41]=[CH:42][CH:43]=2)(=[O:37])=[O:36])[CH2:31][CH2:30]1>>[CH3:28][N:29]1[CH2:34][CH2:33][N:32]([S:35]([C:38]2[CH:39]=[C:40]([NH:44][C:25]([C:24]3[CH:23]=[N:22][N:15]4[C:16]([C:18]([F:21])([F:20])[F:19])=[CH:17][C:12]([C:4]5[CH:5]=[CH:6][C:7]([C:8]([F:11])([F:9])[F:10])=[C:2]([CH3:1])[CH:3]=5)=[N:13][C:14]=34)=[O:26])[CH:41]=[CH:42][CH:43]=2)(=[O:37])=[O:36])[CH2:31][CH2:30]1

Participants

3

Reactant 2

HCID 31976483-(4-Methylpiperazine-1-sulfonyl)anilineHCID 866071145-(3-Methyl-4-trifluoromethyl-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid

Product 1

HCID 87769137HCID 87769137, compound

Procedure

The title compound was prepared from 5-(3-methyl-4-trifluoromethyl-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (example C.8) and 3-(4-methyl-piperazine-1-sulfonyl)-phenylamine [CAS 436095-35-1] according to general procedure II. Yellow solid. MS (ISP) 627.4 [(M+H)+]; mp 199° C.

Sources & evidence

ORD record
ord-39d5c155e4654b7eb112aa9d8f07babc
Source dataset
uspto-grants-2008_05
Patent number
US07378417B2

Reaction notes

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