3-Amino-N-ethylbenzene-1-sulfonamide → HCID 87768941, compound

HRID 2224433Notes

Reaction equation

HRID 2224433 reaction equation
[CH2:1]([O:3][C:4]1[CH:5]=[C:6]([C:14]2[CH:19]=[C:18]([C:20]([F:23])([F:22])[F:21])[N:17]3[N:24]=[CH:25][C:26]([C:27]([OH:29])=O)=[C:16]3[N:15]=2)[CH:7]=[CH:8][C:9]=1[C:10]([F:13])([F:12])[F:11])[CH3:2].[NH2:30][C:31]1[CH:32]=[C:33]([S:37]([NH:40][CH2:41][CH3:42])(=[O:39])=[O:38])[CH:34]=[CH:35][CH:36]=1>>[CH2:41]([NH:40][S:37]([C:33]1[CH:32]=[C:31]([NH:30][C:27]([C:26]2[CH:25]=[N:24][N:17]3[C:18]([C:20]([F:22])([F:23])[F:21])=[CH:19][C:14]([C:6]4[CH:7]=[CH:8][C:9]([C:10]([F:12])([F:11])[F:13])=[C:4]([O:3][CH2:1][CH3:2])[CH:5]=4)=[N:15][C:16]=23)=[O:29])[CH:36]=[CH:35][CH:34]=1)(=[O:39])=[O:38])[CH3:42]

Participants

3

Reactant 2

HCID 72048913-Amino-N-ethylbenzene-1-sulfonamideHCID 866071135-(3-Ethoxy-4-trifluoromethyl-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid

Product 1

HCID 87768941HCID 87768941, compound

Procedure

The title compound was prepared from 5-(3-ethoxy-4-trifluoromethyl-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (example C.11) and 3-amino-N-ethyl-benzenesulfonamide [CAS 56445-08-0] according to general procedure II. Yellow solid. MS (ISP) 600.0 [(M−H)−]; mp 226° C.

Sources & evidence

ORD record
ord-cf4a1d8ca55e4a32b156f7565e5d5393
Source dataset
uspto-grants-2008_05
Patent number
US07378417B2

Reaction notes

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