Benzenesulfonamide, 3-amino- → HCID 11699323, compound

HRID 2224435Notes

Reaction equation

HRID 2224435 reaction equation
[F:1][CH:2]([F:26])[C:3]1[N:8]2[N:9]=[CH:10][C:11]([C:12]([OH:14])=O)=[C:7]2[N:6]=[C:5]([C:15]2[CH:20]=[CH:19][C:18]([C:21]([F:24])([F:23])[F:22])=[C:17]([CH3:25])[CH:16]=2)[CH:4]=1.[S:27]([C:31]1[CH:32]=[C:33]([NH2:37])[CH:34]=[CH:35][CH:36]=1)(=[O:30])(=[O:29])[NH2:28]>>[S:27]([C:31]1[CH:32]=[C:33]([NH:37][C:12]([C:11]2[CH:10]=[N:9][N:8]3[C:3]([CH:2]([F:1])[F:26])=[CH:4][C:5]([C:15]4[CH:20]=[CH:19][C:18]([C:21]([F:24])([F:23])[F:22])=[C:17]([CH3:25])[CH:16]=4)=[N:6][C:7]=23)=[O:14])[CH:34]=[CH:35][CH:36]=1)(=[O:29])(=[O:30])[NH2:28]

Participants

3

Reactant 2

HCID 7377Benzenesulfonamide, 3-amino-HCID 66650674HCID 66650674, compound

Product 1

HCID 11699323HCID 11699323, compound

Procedure

The title compound was prepared from 7-difluoromethyl-5-(3-methyl-4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (example C.5) and 3-sulfamoyl-phenylamine [commercially available] according to general procedure II. Yellow solid. MS (ISP) 524.0 [(M−H)−]; mp 252° C.

Sources & evidence

ORD record
ord-01931f49eb8d432b8458b58b3f1c59dc
Source dataset
uspto-grants-2008_05
Patent number
US07378417B2

Reaction notes

Loading…