Benzenesulfonamide, 3-amino- → HCID 11656447, compound

HRID 2224437Notes

Reaction equation

HRID 2224437 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:9]2[CH:14]=[C:13]([CH:15]([F:17])[F:16])[N:12]3[N:18]=[CH:19][C:20]([C:21](O)=[O:22])=[C:11]3[N:10]=2)[CH:5]=[CH:6][C:7]=1[Cl:8].[S:24]([C:28]1[CH:29]=[C:30]([NH2:34])[CH:31]=[CH:32][CH:33]=1)(=[O:27])(=[O:26])[NH2:25]>>[S:24]([C:28]1[CH:29]=[C:30]([NH:34][C:21]([C:20]2[CH:19]=[N:18][N:12]3[C:13]([CH:15]([F:16])[F:17])=[CH:14][C:9]([C:4]4[CH:5]=[CH:6][C:7]([Cl:8])=[C:2]([Cl:1])[CH:3]=4)=[N:10][C:11]=23)=[O:22])[CH:31]=[CH:32][CH:33]=1)(=[O:26])(=[O:27])[NH2:25]

Participants

3

Reactant 2

HCID 7377Benzenesulfonamide, 3-amino-HCID 4768478HCID 4768478, compound

Product 1

HCID 11656447HCID 11656447, compound

Procedure

The title compound was prepared from 5-(3,4-dichloro-phenyl)-7-difluoromethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (example C.7) and 3-sulfamoyl-phenylamine [commercially available] according to general procedure II. Yellow solid. MS (ISP) 410.1 [(M−H)−]; mp 306° C.

Sources & evidence

ORD record
ord-378c89ed043f49bf84e4095b018e6e96
Source dataset
uspto-grants-2008_05
Patent number
US07378417B2

Reaction notes

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