HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzenesulfonamide, 3-amino- → 5-(3,4-Dichloro-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid(3-sulfamoyl-phenyl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzenesulfonamide, 3-amino- | HCID 7377 | — |
| Reactant | 5-(3,4-Dichloro-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid | HCID 66650294 | — |
| Product | 5-(3,4-Dichloro-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid(3-sulfamoyl-phenyl)-amide | HCID 11620719 | — |
Reaction Steps
The title compound was prepared from 5-(3,4-dichloro-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (example C.9) and 3-sulfamoyl-phenylamine [commercially available] according to general procedure II. Yellow solid. MS (ISP) 528.0 [(M−H)−]; mp 302° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07378417B2 |
| Source dataset | uspto-grants-2008_05 |
| ORD ID | ord-666bcf66df2e45508cb88f9660239dba |
| Source note | uspto-grants-2008_05 |