Benzenesulfonamide, 3-amino- → HCID 11634328, compound

HRID 2224439Notes

Reaction equation

HRID 2224439 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[C:12]([CH:14]([F:16])[F:15])[N:11]3[N:17]=[CH:18][C:19]([C:20](O)=[O:21])=[C:10]3[N:9]=2)=[CH:4][CH:3]=1.[S:23]([C:27]1[CH:28]=[C:29]([NH2:33])[CH:30]=[CH:31][CH:32]=1)(=[O:26])(=[O:25])[NH2:24]>>[S:23]([C:27]1[CH:28]=[C:29]([NH:33][C:20]([C:19]2[CH:18]=[N:17][N:11]3[C:12]([CH:14]([F:15])[F:16])=[CH:13][C:8]([C:5]4[CH:6]=[CH:7][C:2]([Cl:1])=[CH:3][CH:4]=4)=[N:9][C:10]=23)=[O:21])[CH:30]=[CH:31][CH:32]=1)(=[O:25])(=[O:26])[NH2:24]

Participants

3

Reactant 2

HCID 7377Benzenesulfonamide, 3-amino-HCID 666503265-(4-Chloro-phenyl)-7-difluoromethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid

Product 1

HCID 11634328HCID 11634328, compound

Procedure

The title compound was prepared from 5-(4-chloro-phenyl)-7-difluoromethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (example C.4) and 3-sulfamoyl-phenylamine [commercially available] according to general procedure II. Light yellow solid. MS (ISP) 476.0 [(M−H)−]; mp 278° C.

Sources & evidence

ORD record
ord-f806e80654434be096abaad8c93e2a04
Source dataset
uspto-grants-2008_05
Patent number
US07378417B2

Reaction notes

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