3-Amino-N-(propan-2-yl)benzene-1-sulfonamide → HCID 11649890, compound

HRID 2224448Notes

Reaction equation

HRID 2224448 reaction equation
[F:1][C:2]([F:26])([F:25])[C:3]1[N:8]2[N:9]=[CH:10][C:11]([C:12](O)=[O:13])=[C:7]2[N:6]=[C:5]([C:15]2[CH:20]=[CH:19][C:18]([C:21]([F:24])([F:23])[F:22])=[CH:17][CH:16]=2)[CH:4]=1.[NH2:27][C:28]1[CH:29]=[C:30]([S:34]([NH:37][CH:38]([CH3:40])[CH3:39])(=[O:36])=[O:35])[CH:31]=[CH:32][CH:33]=1>>[CH:38]([NH:37][S:34]([C:30]1[CH:29]=[C:28]([NH:27][C:12]([C:11]2[CH:10]=[N:9][N:8]3[C:3]([C:2]([F:26])([F:25])[F:1])=[CH:4][C:5]([C:15]4[CH:20]=[CH:19][C:18]([C:21]([F:24])([F:22])[F:23])=[CH:17][CH:16]=4)=[N:6][C:7]=23)=[O:13])[CH:33]=[CH:32][CH:31]=1)(=[O:36])=[O:35])([CH3:40])[CH3:39]

Participants

3

Reactant 2

HCID 167921413-Amino-N-(propan-2-yl)benzene-1-sulfonamideHCID 866071127-Trifluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid

Product 1

HCID 11649890HCID 11649890, compound

Procedure

The title compound was prepared from 7-trifluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (example C.2) and 3-amino-N-isopropyl-benzenesulfonamide [CAS 118837-66-4] according to general procedure II. Yellow solid. MS (ISP) 570.2 [(M−H)−]; mp 222° C.

Sources & evidence

ORD record
ord-dd7f318b55f34c438192af819d8ae06a
Source dataset
uspto-grants-2008_05
Patent number
US07378417B2

Reaction notes

Loading…