HRID2224451

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID24706735

未命名化合物

结构：O=C(O)c1cnn2c(C(F)F)cc(-c3ccc(C(F)(F)F)cc3)nc12

HCID66650268

未命名化合物

PRODUCTS

生成物

结构：O=C(Nc1cccc(S(=O)(=O)NCC(F)(F)F)c1)c1cnn2c(C(F)F)cc(-c3ccc(C(F)(F)F)cc3)nc12

HCID11512702

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from 7-difluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (example C.1) and 3-amino-N-(2,2,2-trifluoroethyl)-benzenesulfonamide [synthesis: see part aniline derivatives] according to general procedure II. Yellow solid. MS (ISP) 592.0 [(M−H)−]; mp 257° C.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-2e148161f24d4e118305defc05667402
来源数据集: uspto-grants-2008_05
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07378417B2
来源说明: uspto-grants-2008_05

反应 SMILES

[F:1][CH:2]([F:25])[C:3]1[N:8]2[N:9]=[CH:10][C:11]([C:12]([OH:14])=O)=[C:7]2[N:6]=[C:5]([C:15]2[CH:20]=[CH:19][C:18]([C:21]([F:24])([F:23])[F:22])=[CH:17][CH:16]=2)[CH:4]=1.[NH2:26][C:27]1[CH:28]=[C:29]([S:33]([NH:36][CH2:37][C:38]([F:41])([F:40])[F:39])(=[O:35])=[O:34])[CH:30]=[CH:31][CH:32]=1>>[F:41][C:38]([F:39])([F:40])[CH2:37][NH:36][S:33]([C:29]1[CH:28]=[C:27]([NH:26][C:12]([C:11]2[CH:10]=[N:9][N:8]3[C:3]([CH:2]([F:25])[F:1])=[CH:4][C:5]([C:15]4[CH:16]=[CH:17][C:18]([C:21]([F:22])([F:23])[F:24])=[CH:19][CH:20]=4)=[N:6][C:7]=23)=[O:14])[CH:32]=[CH:31][CH:30]=1)(=[O:35])=[O:34]