HRID2224457

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID5303061

3-amino-N-cyclopropylbenzenesulfonamide

C9H12N2O2S

HCID86607114

未命名化合物

PRODUCTS

产物

HCID11577854

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from 5-(3-methyl-4-trifluoromethyl-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (example C.8) and 3-amino-N-cyclopropyl-benzenesulfonamide [CAS 459434-39-0] according to general procedure II. Yellow solid. MS (ISP) 582.0 [(M−H)−]; mp 201° C.

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-ed940cc581804917a05c86011d2dd3e4
来源数据集: uspto-grants-2008_05
DOI: 10.6084/m9.figshare.5104873.v1
专利号: US07378417B2
来源说明: uspto-grants-2008_05

反应SMILES

[CH3:1][C:2]1[CH:3]=[C:4]([C:12]2[CH:17]=[C:16]([C:18]([F:21])([F:20])[F:19])[N:15]3[N:22]=[CH:23][C:24]([C:25](O)=[O:26])=[C:14]3[N:13]=2)[CH:5]=[CH:6][C:7]=1[C:8]([F:11])([F:10])[F:9].[NH2:28][C:29]1[CH:30]=[C:31]([S:35]([NH:38][CH:39]2[CH2:41][CH2:40]2)(=[O:37])=[O:36])[CH:32]=[CH:33][CH:34]=1>>[CH:39]1([NH:38][S:35]([C:31]2[CH:30]=[C:29]([NH:28][C:25]([C:24]3[CH:23]=[N:22][N:15]4[C:16]([C:18]([F:21])([F:20])[F:19])=[CH:17][C:12]([C:4]5[CH:5]=[CH:6][C:7]([C:8]([F:11])([F:9])[F:10])=[C:2]([CH3:1])[CH:3]=5)=[N:13][C:14]=34)=[O:26])[CH:34]=[CH:33][CH:32]=2)(=[O:37])=[O:36])[CH2:41][CH2:40]1