3-amino-N-cyclopropylbenzenesulfonamide → HCID 11635516, compound

HRID 2224458Notes

Reaction equation

HRID 2224458 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:9]2[CH:14]=[C:13]([C:15]([F:18])([F:17])[F:16])[N:12]3[N:19]=[CH:20][C:21]([C:22]([OH:24])=O)=[C:11]3[N:10]=2)[CH:5]=[CH:6][C:7]=1[Cl:8].[NH2:25][C:26]1[CH:27]=[C:28]([S:32]([NH:35][CH:36]2[CH2:38][CH2:37]2)(=[O:34])=[O:33])[CH:29]=[CH:30][CH:31]=1>>[CH:36]1([NH:35][S:32]([C:28]2[CH:27]=[C:26]([NH:25][C:22]([C:21]3[CH:20]=[N:19][N:12]4[C:13]([C:15]([F:17])([F:16])[F:18])=[CH:14][C:9]([C:4]5[CH:5]=[CH:6][C:7]([Cl:8])=[C:2]([Cl:1])[CH:3]=5)=[N:10][C:11]=34)=[O:24])[CH:31]=[CH:30][CH:29]=2)(=[O:34])=[O:33])[CH2:38][CH2:37]1

Participants

3

Reactant 2

HCID 53030613-amino-N-cyclopropylbenzenesulfonamideHCID 666502945-(3,4-Dichloro-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid

Product 1

HCID 11635516HCID 11635516, compound

Procedure

The title compound was prepared from 5-(3,4-dichloro-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (example C.9) and 3-amino-N-cyclopropyl-benzenesulfonamide [CAS 459434-39-0] according to general procedure II. Yellow solid. MS (ISP) 567.9 [(M−H)−]; mp 248° C.

Sources & evidence

ORD record
ord-dff2c93c81dc4fa4b8e9ec994d492561
Source dataset
uspto-grants-2008_05
Patent number
US07378417B2

Reaction notes

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