3-amino-N-cyclopropylbenzenesulfonamide → HCID 11512475, compound

HRID 2224461Notes

Reaction equation

HRID 2224461 reaction equation
[F:1][CH:2]([F:26])[C:3]1[N:8]2[N:9]=[CH:10][C:11]([C:12](O)=[O:13])=[C:7]2[N:6]=[C:5]([C:15]2[CH:20]=[CH:19][C:18]([C:21]([F:24])([F:23])[F:22])=[C:17]([CH3:25])[CH:16]=2)[CH:4]=1.[NH2:27][C:28]1[CH:29]=[C:30]([S:34]([NH:37][CH:38]2[CH2:40][CH2:39]2)(=[O:36])=[O:35])[CH:31]=[CH:32][CH:33]=1>>[CH:38]1([NH:37][S:34]([C:30]2[CH:29]=[C:28]([NH:27][C:12]([C:11]3[CH:10]=[N:9][N:8]4[C:3]([CH:2]([F:1])[F:26])=[CH:4][C:5]([C:15]5[CH:20]=[CH:19][C:18]([C:21]([F:23])([F:24])[F:22])=[C:17]([CH3:25])[CH:16]=5)=[N:6][C:7]=34)=[O:13])[CH:33]=[CH:32][CH:31]=2)(=[O:36])=[O:35])[CH2:40][CH2:39]1

Participants

3

Reactant 2

HCID 53030613-amino-N-cyclopropylbenzenesulfonamideHCID 66650674HCID 66650674, compound

Product 1

HCID 11512475HCID 11512475, compound

Procedure

The title compound was prepared from 7-difluoromethyl-5-(3-methyl-4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (example C.5) and 3-amino-N-cyclopropyl-benzenesulfonamide [CAS 459434-39-0] according to general procedure II. Light yellow solid. MS (ISP) 564.2 [(M−H)−]; mp 199° C.

Sources & evidence

ORD record
ord-62b55557ca274c74a3791962c5e6401a
Source dataset
uspto-grants-2008_05
Patent number
US07378417B2

Reaction notes

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