HCID 4768478, compound → HCID 11563027, compound

HRID 2224462Notes

Reaction equation

HRID 2224462 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:9]2[CH:14]=[C:13]([CH:15]([F:17])[F:16])[N:12]3[N:18]=[CH:19][C:20]([C:21](O)=[O:22])=[C:11]3[N:10]=2)[CH:5]=[CH:6][C:7]=1[Cl:8].[NH2:24][C:25]1[CH:26]=[C:27]([S:31]([NH:34][CH:35]2[CH2:37][CH2:36]2)(=[O:33])=[O:32])[CH:28]=[CH:29][CH:30]=1>>[CH:35]1([NH:34][S:31]([C:27]2[CH:26]=[C:25]([NH:24][C:21]([C:20]3[CH:19]=[N:18][N:12]4[C:13]([CH:15]([F:16])[F:17])=[CH:14][C:9]([C:4]5[CH:5]=[CH:6][C:7]([Cl:8])=[C:2]([Cl:1])[CH:3]=5)=[N:10][C:11]=34)=[O:22])[CH:30]=[CH:29][CH:28]=2)(=[O:33])=[O:32])[CH2:37][CH2:36]1

Participants

3

Reactant 2

HCID 4768478HCID 4768478, compoundHCID 53030613-amino-N-cyclopropylbenzenesulfonamide

Product 1

HCID 11563027HCID 11563027, compound

Procedure

The title compound was prepared from 5-(3,4-dichloro-phenyl)-7-difluoromethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (example C.7) and 3-amino-N-cyclopropyl-benzenesulfonamide [CAS 459434-39-0] according to general procedure II. Light yellow solid. MS (ISP) 550.0 [(M−H)−]; mp 254° C.

Sources & evidence

ORD record
ord-b7c8e3932f9f4ebbbcea27896aa17657
Source dataset
uspto-grants-2008_05
Patent number
US07378417B2

Reaction notes

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