HRID2224464

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID16788583

未命名化合物

结构：O=C(O)c1cnn2c(C(F)(F)F)cc(-c3ccc(C(F)(F)F)cc3)nc12

HCID86607112

未命名化合物

PRODUCTS

生成物

结构：O=C(Nc1cccc(S(=O)(=O)NCC2CC2)c1)c1cnn2c(C(F)(F)F)cc(-c3ccc(C(F)(F)F)cc3)nc12

HCID11599569

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from 7-trifluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (example C.2) and 3-amino-N-cyclopropylmethyl-benzenesulfonamide (example B.2) according to general procedure II. Yellow solid. MS (ISP) 582.1 [(M−H)−]; mp 234° C.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-f9a429d75a31454c8978c0e8b7cc7204
来源数据集: uspto-grants-2008_05
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07378417B2
来源说明: uspto-grants-2008_05

反应 SMILES

[F:1][C:2]([F:26])([F:25])[C:3]1[N:8]2[N:9]=[CH:10][C:11]([C:12](O)=[O:13])=[C:7]2[N:6]=[C:5]([C:15]2[CH:20]=[CH:19][C:18]([C:21]([F:24])([F:23])[F:22])=[CH:17][CH:16]=2)[CH:4]=1.[NH2:27][C:28]1[CH:29]=[C:30]([S:34]([NH:37][CH2:38][CH:39]2[CH2:41][CH2:40]2)(=[O:36])=[O:35])[CH:31]=[CH:32][CH:33]=1>>[CH:39]1([CH2:38][NH:37][S:34]([C:30]2[CH:29]=[C:28]([NH:27][C:12]([C:11]3[CH:10]=[N:9][N:8]4[C:3]([C:2]([F:26])([F:25])[F:1])=[CH:4][C:5]([C:15]5[CH:20]=[CH:19][C:18]([C:21]([F:24])([F:22])[F:23])=[CH:17][CH:16]=5)=[N:6][C:7]=34)=[O:13])[CH:33]=[CH:32][CH:31]=2)(=[O:36])=[O:35])[CH2:40][CH2:41]1