Ethanol, 2-[(3-aminophenyl)sulfonyl]- → HCID 11526919, compound

HRID 2224488Notes

Reaction equation

HRID 2224488 reaction equation
[F:1][C:2]([F:26])([F:25])[C:3]1[N:8]2[N:9]=[CH:10][C:11]([C:12](O)=[O:13])=[C:7]2[N:6]=[C:5]([C:15]2[CH:20]=[CH:19][C:18]([C:21]([F:24])([F:23])[F:22])=[CH:17][CH:16]=2)[CH:4]=1.[OH:27][CH2:28][CH2:29][S:30]([C:33]1[CH:34]=[C:35]([CH:37]=[CH:38][CH:39]=1)[NH2:36])(=[O:32])=[O:31]>>[OH:27][CH2:28][CH2:29][S:30]([C:33]1[CH:34]=[C:35]([NH:36][C:12]([C:11]2[CH:10]=[N:9][N:8]3[C:3]([C:2]([F:26])([F:25])[F:1])=[CH:4][C:5]([C:15]4[CH:20]=[CH:19][C:18]([C:21]([F:24])([F:22])[F:23])=[CH:17][CH:16]=4)=[N:6][C:7]=23)=[O:13])[CH:37]=[CH:38][CH:39]=1)(=[O:31])=[O:32]

Participants

3

Reactant 2

HCID 78905Ethanol, 2-[(3-aminophenyl)sulfonyl]-HCID 866071127-Trifluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid

Product 1

HCID 11526919HCID 11526919, compound

Procedure

The title compound was prepared from 7-trifluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (example C.1) and 3-(2-hydroxy-ethanesulfonyl)-aniline [commercially available] according to general procedure II. Yellow solid. MS (ISP) 559.4 [(M+H)+]; mp 237° C.

Sources & evidence

ORD record
ord-becfcc0eb04745f2ae9d025325770d70
Source dataset
uspto-grants-2008_05
Patent number
US07378417B2

Reaction notes

Loading…