3-Amino-N-pyridin-3-ylmethyl-benzenesulfonamide → HCID 11714158, compound

HRID 2224501Notes

Reaction equation

HRID 2224501 reaction equation
[F:1][CH:2]([F:25])[C:3]1[N:8]2[N:9]=[CH:10][C:11]([C:12](O)=[O:13])=[C:7]2[N:6]=[C:5]([C:15]2[CH:20]=[CH:19][C:18]([C:21]([F:24])([F:23])[F:22])=[CH:17][CH:16]=2)[CH:4]=1.[NH2:26][C:27]1[CH:28]=[C:29]([S:33]([NH:36][CH2:37][C:38]2[CH:39]=[N:40][CH:41]=[CH:42][CH:43]=2)(=[O:35])=[O:34])[CH:30]=[CH:31][CH:32]=1>>[N:40]1[CH:41]=[CH:42][CH:43]=[C:38]([CH2:37][NH:36][S:33]([C:29]2[CH:28]=[C:27]([NH:26][C:12]([C:11]3[CH:10]=[N:9][N:8]4[C:3]([CH:2]([F:1])[F:25])=[CH:4][C:5]([C:15]5[CH:20]=[CH:19][C:18]([C:21]([F:24])([F:23])[F:22])=[CH:17][CH:16]=5)=[N:6][C:7]=34)=[O:13])[CH:32]=[CH:31][CH:30]=2)(=[O:35])=[O:34])[CH:39]=1

Participants

3

Reactant 2

HCID 31976503-Amino-N-pyridin-3-ylmethyl-benzenesulfonamideHCID 666502687-Difluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid

Product 1

HCID 11714158HCID 11714158, compound

Procedure

The title compound was prepared from 7-difluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (example C.1) and 3-amino-N-pyridin-3-ylmethyl-benzenesulfonamide (example B.5) according to general procedure II. Yellow solid. MS (ISP) 603.2 [(M+H+]; mp 256° C.

Sources & evidence

ORD record
ord-85d6f3fc74b74450a0d8034e2b1b8806
Source dataset
uspto-grants-2008_05
Patent number
US07378417B2

Reaction notes

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