HCID 54943777, compound → HCID 11585315, compound

HRID 2224505Notes

Reaction equation

HRID 2224505 reaction equation
[F:1][CH:2]([F:25])[C:3]1[N:8]2[N:9]=[CH:10][C:11]([C:12](O)=[O:13])=[C:7]2[N:6]=[C:5]([C:15]2[CH:20]=[CH:19][C:18]([C:21]([F:24])([F:23])[F:22])=[CH:17][CH:16]=2)[CH:4]=1.[NH2:26][C:27]1[CH:28]=[C:29]([S:33]([NH:36][CH2:37][CH2:38][C:39]2[CH:44]=[CH:43][N:42]=[CH:41][CH:40]=2)(=[O:35])=[O:34])[CH:30]=[CH:31][CH:32]=1>>[N:42]1[CH:43]=[CH:44][C:39]([CH2:38][CH2:37][NH:36][S:33]([C:29]2[CH:28]=[C:27]([NH:26][C:12]([C:11]3[CH:10]=[N:9][N:8]4[C:3]([CH:2]([F:25])[F:1])=[CH:4][C:5]([C:15]5[CH:16]=[CH:17][C:18]([C:21]([F:24])([F:22])[F:23])=[CH:19][CH:20]=5)=[N:6][C:7]=34)=[O:13])[CH:32]=[CH:31][CH:30]=2)(=[O:35])=[O:34])=[CH:40][CH:41]=1

Participants

3

Reactant 2

HCID 54943777HCID 54943777, compoundHCID 666502687-Difluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid

Product 1

HCID 11585315HCID 11585315, compound

Procedure

The title compound was prepared from 7-difluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (example C.1) and 3-amino-N-(2-pyridin-4-yl-ethyl)-benzenesulfonamide (example B.7) according to general procedure II. Yellow solid. MS (ISP) 615.3 [(M−H−]; mp 238° C.

Sources & evidence

ORD record
ord-1013be17ce414d53a7e535c43dc5eb6a
Source dataset
uspto-grants-2008_05
Patent number
US07378417B2

Reaction notes

Loading…