3-(Methylsulphonyl)aniline → HCID 11576213, compound

HRID 2224543Notes

Reaction equation

HRID 2224543 reaction equation
[F:1][C:2]([F:22])([F:21])[C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:14]=[CH:13][N:12]3[N:15]=[CH:16][C:17]([C:18]([OH:20])=O)=[C:11]3[N:10]=2)=[CH:5][CH:4]=1.[CH3:23][S:24]([C:27]1[CH:28]=[C:29]([NH2:33])[CH:30]=[CH:31][CH:32]=1)(=[O:26])=[O:25]>>[CH3:23][S:24]([C:27]1[CH:28]=[C:29]([NH:33][C:18]([C:17]2[CH:16]=[N:15][N:12]3[CH:13]=[CH:14][C:9]([C:6]4[CH:5]=[CH:4][C:3]([C:2]([F:1])([F:22])[F:21])=[CH:8][CH:7]=4)=[N:10][C:11]=23)=[O:20])[CH:30]=[CH:31][CH:32]=1)(=[O:25])=[O:26]

Participants

3

Reactant 2

HCID 4280293-(Methylsulphonyl)anilineHCID 66650290HCID 66650290, compound

Product 1

HCID 11576213HCID 11576213, compound

Procedure

The title compound was prepared from 5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (example C.23) and 3-methanesulfonyl-phenylamine according to general procedure II. Pale-yellow solid. MS (ISP) 461.3 [(M+H)+]; mp 254-255° C.

Sources & evidence

ORD record
ord-39cc45f45dc14cfeacd107b3eb258692
Source dataset
uspto-grants-2008_05
Patent number
US07378417B2

Reaction notes

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