3-(Methylsulphonyl)aniline → HCID 11546688, compound

HRID 2224545Notes

Reaction equation

HRID 2224545 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[C:12]([CH3:14])[N:11]3[N:15]=[CH:16][C:17]([C:18]([OH:20])=O)=[C:10]3[N:9]=2)=[CH:4][CH:3]=1.[CH3:21][S:22]([C:25]1[CH:26]=[C:27]([NH2:31])[CH:28]=[CH:29][CH:30]=1)(=[O:24])=[O:23]>>[CH3:21][S:22]([C:25]1[CH:26]=[C:27]([NH:31][C:18]([C:17]2[CH:16]=[N:15][N:11]3[C:12]([CH3:14])=[CH:13][C:8]([C:5]4[CH:4]=[CH:3][C:2]([Cl:1])=[CH:7][CH:6]=4)=[N:9][C:10]=23)=[O:20])[CH:28]=[CH:29][CH:30]=1)(=[O:23])=[O:24]

Participants

3

Reactant 2

HCID 4280293-(Methylsulphonyl)anilineHCID 66650321HCID 66650321, compound

Product 1

HCID 11546688HCID 11546688, compound

Procedure

The title compound was prepared from 5-(4-chloro-phenyl)-7-methyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (example C.24) and 3-methanesulfonyl-phenylamine according to general procedure II. Pale-yellow solid. MS (ISP) 441.3 [(M+H)+]; mp 250-251° C.

Sources & evidence

ORD record
ord-305a96fc7f53438d94d7510312234847
Source dataset
uspto-grants-2008_05
Patent number
US07378417B2

Reaction notes

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