3-(Methylsulphonyl)aniline → HCID 11712582, compound

HRID 2224548Notes

Reaction equation

HRID 2224548 reaction equation
[CH3:1][C:2]1[N:7]2[N:8]=[CH:9][C:10]([C:11]([OH:13])=O)=[C:6]2[N:5]=[C:4]([C:14]2[CH:19]=[CH:18][C:17]([C:20]([F:23])([F:22])[F:21])=[CH:16][CH:15]=2)[CH:3]=1.[CH3:24][S:25]([C:28]1[CH:29]=[C:30]([NH2:34])[CH:31]=[CH:32][CH:33]=1)(=[O:27])=[O:26]>>[CH3:24][S:25]([C:28]1[CH:29]=[C:30]([NH:34][C:11]([C:10]2[CH:9]=[N:8][N:7]3[C:2]([CH3:1])=[CH:3][C:4]([C:14]4[CH:19]=[CH:18][C:17]([C:20]([F:22])([F:23])[F:21])=[CH:16][CH:15]=4)=[N:5][C:6]=23)=[O:13])[CH:31]=[CH:32][CH:33]=1)(=[O:26])=[O:27]

Participants

3

Reactant 2

HCID 4280293-(Methylsulphonyl)anilineHCID 66650358HCID 66650358, compound

Product 1

HCID 11712582HCID 11712582, compound

Procedure

The title compound was prepared from 7-methyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (example C.25) and 3-methanesulfonyl-phenylamine according to general procedure II. Pale-yellow solid. MS (ISP) 475.1 [(M+H)+]; mp 198-200° C.

Sources & evidence

ORD record
ord-d5bc456e23024cf59b8e4aad1c3af97c
Source dataset
uspto-grants-2008_05
Patent number
US07378417B2

Reaction notes

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