Benzenesulfonamide, 3-amino- → HCID 69292772, compound

HRID 2224549Notes

Reaction equation

HRID 2224549 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[C:12]([CH2:14][CH3:15])[N:11]3[N:16]=[CH:17][C:18]([C:19](O)=[O:20])=[C:10]3[N:9]=2)=[CH:4][CH:3]=1.[NH2:22][C:23]1[CH:24]=[C:25]([S:29]([NH2:32])(=[O:31])=[O:30])[CH:26]=[CH:27][CH:28]=1>>[S:29]([C:25]1[CH:24]=[C:23]([NH:22][C:19]([C:18]2[CH:17]=[N:16][N:11]3[C:12]([CH2:14][CH3:15])=[CH:13][C:8]([C:5]4[CH:6]=[CH:7][C:2]([Cl:1])=[CH:3][CH:4]=4)=[N:9][C:10]=23)=[O:20])[CH:28]=[CH:27][CH:26]=1)(=[O:30])(=[O:31])[NH2:32]

Participants

3

Reactant 2

HCID 7377Benzenesulfonamide, 3-amino-HCID 66650467HCID 66650467, compound

Product 1

HCID 69292772HCID 69292772, compound

Procedure

The title compound was prepared from 5-(4-chloro-phenyl)-7-ethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (example C.26) and 3-amino-benzenesulfonamide according to general procedure II. Pale-yellow solid. MS (ISN) 454.3 [(M−H)−]; mp 252-253° C.

Sources & evidence

ORD record
ord-5fd639faebcf478294bb85c5eab689df
Source dataset
uspto-grants-2008_05
Patent number
US07378417B2

Reaction notes

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