3-(Methylsulphonyl)aniline → HCID 11669678, compound

HRID 2224550Notes

Reaction equation

HRID 2224550 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[C:12]([CH2:14][CH3:15])[N:11]3[N:16]=[CH:17][C:18]([C:19](O)=[O:20])=[C:10]3[N:9]=2)=[CH:4][CH:3]=1.[CH3:22][S:23]([C:26]1[CH:27]=[C:28]([NH2:32])[CH:29]=[CH:30][CH:31]=1)(=[O:25])=[O:24]>>[CH3:22][S:23]([C:26]1[CH:27]=[C:28]([NH:32][C:19]([C:18]2[CH:17]=[N:16][N:11]3[C:12]([CH2:14][CH3:15])=[CH:13][C:8]([C:5]4[CH:4]=[CH:3][C:2]([Cl:1])=[CH:7][CH:6]=4)=[N:9][C:10]=23)=[O:20])[CH:29]=[CH:30][CH:31]=1)(=[O:24])=[O:25]

Participants

3

Reactant 2

HCID 4280293-(Methylsulphonyl)anilineHCID 66650467HCID 66650467, compound

Product 1

HCID 11669678HCID 11669678, compound

Procedure

The title compound was prepared from 5-(4-chloro-phenyl)-7-ethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (example C.26) and 3-methanesulfonyl-phenylamine according to general procedure II. Pale-yellow solid. MS (ISP) 455.92 [(M+H)+]; mp 230-232° C.

Sources & evidence

ORD record
ord-fc73d50b8dc1410bbd62b1b487dbf262
Source dataset
uspto-grants-2008_05
Patent number
US07378417B2

Reaction notes

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