3-Amino-n-(2-hydroxy-1,1-dimethyl-ethyl)-benzenesulfonamide → HCID 69292985, compound

HRID 2224551Notes

Reaction equation

HRID 2224551 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[C:12]([CH2:14][CH3:15])[N:11]3[N:16]=[CH:17][C:18]([C:19](O)=[O:20])=[C:10]3[N:9]=2)=[CH:4][CH:3]=1.[NH2:22][C:23]1[CH:24]=[C:25]([S:29]([NH:32][C:33]([CH3:37])([CH3:36])[CH2:34][OH:35])(=[O:31])=[O:30])[CH:26]=[CH:27][CH:28]=1>>[OH:35][CH2:34][C:33]([NH:32][S:29]([C:25]1[CH:24]=[C:23]([NH:22][C:19]([C:18]2[CH:17]=[N:16][N:11]3[C:12]([CH2:14][CH3:15])=[CH:13][C:8]([C:5]4[CH:4]=[CH:3][C:2]([Cl:1])=[CH:7][CH:6]=4)=[N:9][C:10]=23)=[O:20])[CH:28]=[CH:27][CH:26]=1)(=[O:31])=[O:30])([CH3:37])[CH3:36]

Participants

3

Reactant 2

HCID 434986663-Amino-n-(2-hydroxy-1,1-dimethyl-ethyl)-benzenesulfonamideHCID 66650467HCID 66650467, compound

Product 1

HCID 69292985HCID 69292985, compound

Procedure

The title compound was prepared from 5-(4-chloro-phenyl)-7-ethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (example C.26) and 3-amino-N-(2-hydroxy-1,1-dimethyl-ethyl)-benzenesulfonamide (example B.8) according to general procedure II. Pale-yellow solid. MS (ISP) 528.0 [(M+H)+]; mp 239-240° C.

Sources & evidence

ORD record
ord-aace9ba76fee49e1ab69786d5d75aa3a
Source dataset
uspto-grants-2008_05
Patent number
US07378417B2

Reaction notes

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