HCID 62522906, compound → HCID 69292069, compound

HRID 2224560Notes

Reaction equation

HRID 2224560 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[C:12]([CH:14]3[CH2:16][CH2:15]3)[N:11]3[N:17]=[CH:18][C:19]([C:20]([OH:22])=O)=[C:10]3[N:9]=2)=[CH:4][CH:3]=1.[NH2:23][C:24]1[CH:25]=[C:26]([S:30]([NH:33][C:34]2([CH2:39][OH:40])[CH2:38][CH2:37][CH2:36][CH2:35]2)(=[O:32])=[O:31])[CH:27]=[CH:28][CH:29]=1>>[OH:40][CH2:39][C:34]1([NH:33][S:30]([C:26]2[CH:25]=[C:24]([NH:23][C:20]([C:19]3[CH:18]=[N:17][N:11]4[C:12]([CH:14]5[CH2:16][CH2:15]5)=[CH:13][C:8]([C:5]5[CH:4]=[CH:3][C:2]([Cl:1])=[CH:7][CH:6]=5)=[N:9][C:10]=34)=[O:22])[CH:29]=[CH:28][CH:27]=2)(=[O:32])=[O:31])[CH2:38][CH2:37][CH2:36][CH2:35]1

Participants

3

Reactant 2

HCID 62522906HCID 62522906, compoundHCID 666504695-(4-Chloro-phenyl)-7-cyclopropyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid

Product 1

HCID 69292069HCID 69292069, compound

Procedure

The title compound was prepared from 5-(4-chloro-phenyl)-7-cyclopropyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (example C.28) and 3-amino-N-(1-hydroxymethyl-cyclopentyl)-benzenesulfonamide (example B.13) according to general procedure II. Pale-yellow solid. MS (ISP) 566.3 [(M+H)+]; mp 255-257° C.

Sources & evidence

ORD record
ord-9f717fc94b8443d1ab844d6361701a73
Source dataset
uspto-grants-2008_05
Patent number
US07378417B2

Reaction notes

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