HCID 43498657, compound → HCID 69292050, compound

HRID 2224566Notes

Reaction equation

HRID 2224566 reaction equation
[CH:1]1([C:4]2[N:9]3[N:10]=[CH:11][C:12]([C:13](O)=[O:14])=[C:8]3[N:7]=[C:6]([C:16]3[CH:21]=[CH:20][C:19]([C:22]([F:25])([F:24])[F:23])=[CH:18][CH:17]=3)[CH:5]=2)[CH2:3][CH2:2]1.[NH2:26][C:27]1[CH:28]=[C:29]([S:34]([NH:37][C:38]([CH3:42])([CH3:41])[CH2:39][OH:40])(=[O:36])=[O:35])[CH:30]=[CH:31][C:32]=1[CH3:33]>>[OH:40][CH2:39][C:38]([NH:37][S:34]([C:29]1[CH:30]=[CH:31][C:32]([CH3:33])=[C:27]([NH:26][C:13]([C:12]2[CH:11]=[N:10][N:9]3[C:4]([CH:1]4[CH2:2][CH2:3]4)=[CH:5][C:6]([C:16]4[CH:17]=[CH:18][C:19]([C:22]([F:25])([F:24])[F:23])=[CH:20][CH:21]=4)=[N:7][C:8]=23)=[O:14])[CH:28]=1)(=[O:36])=[O:35])([CH3:42])[CH3:41]

Participants

3

Reactant 2

HCID 43498657HCID 43498657, compoundHCID 666503207-Cyclopropyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid

Product 1

HCID 69292050HCID 69292050, compound

Procedure

The title compound was prepared from 7-cyclopropyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (example C.29) and 3-amino-N-(2-hydroxy-1,1-dimethyl-ethyl)-4-methyl-benzenesulfonamide (example B. 11) according to general procedure II. Pale-yellow solid. Mp 232-233° C.

Sources & evidence

ORD record
ord-2e2bc889824b4ff6bddccd4926b72cf0
Source dataset
uspto-grants-2008_05
Patent number
US07378417B2

Reaction notes

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