3-(Methylsulphonyl)aniline → HCID 11641183, compound

HRID 2224567Notes

Reaction equation

HRID 2224567 reaction equation
[Cl:1][C:2]1[N:7]2[N:8]=[CH:9][C:10]([C:11](Cl)=[O:12])=[C:6]2[N:5]=[C:4]([C:14]2[CH:19]=[CH:18][C:17]([Cl:20])=[CH:16][CH:15]=2)[CH:3]=1.[CH3:21][S:22]([C:25]1[CH:26]=[C:27]([NH2:31])[CH:28]=[CH:29][CH:30]=1)(=[O:24])=[O:23]>>[CH3:21][S:22]([C:25]1[CH:26]=[C:27]([NH:31][C:11]([C:10]2[CH:9]=[N:8][N:7]3[C:2]([Cl:1])=[CH:3][C:4]([C:14]4[CH:19]=[CH:18][C:17]([Cl:20])=[CH:16][CH:15]=4)=[N:5][C:6]=23)=[O:12])[CH:28]=[CH:29][CH:30]=1)(=[O:23])=[O:24]

Participants

3

Reactant 2

HCID 4280293-(Methylsulphonyl)anilineHCID 87767602HCID 87767602, compound

Product 1

HCID 11641183HCID 11641183, compound

Procedure

The title compound was prepared from 7-chloro-5-(4-chloro-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carbonyl chloride and 3-methanesulfonyl-phenylamine according to general procedure II. Pale-yellow solid. MS (ISP) 461.3 [(M+H)+]; mp 253-255° C.

Sources & evidence

ORD record
ord-f335bacfcdab4ad5b5acb2ec68b83e16
Source dataset
uspto-grants-2008_05
Patent number
US07378417B2

Reaction notes

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