Methyl 2-methyl-2-phenylpropanoate → 2-Phenylisobutyric acid

HRID 2224786Notes

Reaction equation

HRID 2224786 reaction equation
[CH3:1][C:2]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)([CH3:7])[C:3]([O:5]C)=[O:4].C1(C(CCC)(CCC)C(OC)=O)C=CC=CC=1>>[CH3:7][C:2]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)([CH3:1])[C:3]([OH:5])=[O:4]

Participants

3

Reactant 2

HCID 143498Methyl 2-methyl-2-phenylpropanoateHCID 11658708Methyl 2-phenyl-2-propylpentanoate

Product 1

HCID 132222-Phenylisobutyric acid

Procedure

The title compound was prepared according to the procedure of Example 1C, substituting the product of Example 9A for the product of Example 1B. 1H NMR (300 MHz, CDCl3): δ 7.33 (m, 5 H), 1.60 (s, 6 H).

Sources & evidence

ORD record
ord-9e4f6d7deae546309b0f98c606a532ba
Source dataset
uspto-grants-2008_05
Patent number
US07378414B2

Reaction notes

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