Methyl 2-phenyl-2-propylpentanoate → 2-(4-Fluorophenyl)-2,5-dimethylhexanoic acid

HRID 2224819Notes

Reaction equation

HRID 2224819 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([CH3:18])([CH2:13][CH2:14][CH:15]([CH3:17])[CH3:16])[C:9]([O:11]C)=[O:10])=[CH:4][CH:3]=1.C1(C(CCC)(CCC)C(OC)=O)C=CC=CC=1>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]([CH3:18])([CH2:13][CH2:14][CH:15]([CH3:16])[CH3:17])[C:9]([OH:11])=[O:10])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 11658708Methyl 2-phenyl-2-propylpentanoateHCID 68872679Methyl 2-(4-fluorophenyl)-2,5-dimethylhexanoate

Product 1

HCID 688699802-(4-Fluorophenyl)-2,5-dimethylhexanoic acid

Procedure

The title compound was prepared according to the procedure of Example 1C, substituting the compound of Example 22B for the compound of Example 1B. 1H NMR (300 MHz, CDCl3): δ 0.86 (t, J=6.43 Hz, 6 H) 1.05 (m, 2 H) 1.51 (m, 4 H) 1.96 (m, 2 H) 7.02 (m, 2 H) 7.34 (m, 2 H).

Sources & evidence

ORD record
ord-a58363c5e34d44c58363e733acb853fb
Source dataset
uspto-grants-2008_05
Patent number
US07378414B2

Reaction notes

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