Methyl 2-phenyl-2-propylpentanoate → 2-(4-Fluorophenyl)-2,5,5-trimethylhexanoic acid

HRID 2224823Notes

Reaction equation

HRID 2224823 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([CH3:19])([CH2:13][CH2:14][C:15]([CH3:18])([CH3:17])[CH3:16])[C:9]([O:11]C)=[O:10])=[CH:4][CH:3]=1.C1(C(CCC)(CCC)C(OC)=O)C=CC=CC=1>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]([CH3:19])([CH2:13][CH2:14][C:15]([CH3:18])([CH3:17])[CH3:16])[C:9]([OH:11])=[O:10])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 11658708Methyl 2-phenyl-2-propylpentanoateHCID 68874795Methyl 2-(4-fluorophenyl)-2,5,5-trimethylhexanoate

Product 1

HCID 688724912-(4-Fluorophenyl)-2,5,5-trimethylhexanoic acid

Procedure

The title compound was prepared according to the procedure of Example 1C, substituting the compound of Example 24A for the compound of Example 1B. 1H NMR (300 MHz, CDCl3): δ 0.86 (s, 9 H) 1.05 (m, 2 H) 1.52 (s, 3 H) 1.91 (m, 2 H) 7.03 (m, 2 H) 7.32 (m, 2 H).

Sources & evidence

ORD record
ord-60ad3e6d9be44daba7713c9d991a525d
Source dataset
uspto-grants-2008_05
Patent number
US07378414B2

Reaction notes

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