HCID 69268623, compound → α-Butyl-α-methylbenzeneacetic acid

Participants

Reaction Steps

A solution of Example 27A (2.45 g, 8.32 mmol) in ethyl acetate (20 mL) was treated with 10% palladium on carbon (0.245 g, 10 weight percent) and stirred under a hydrogen balloon for 72 hours. The vessel was purged with nitrogen gas and the mixture was filtered through a pad of celite and the filtrate was concentrated in vacuo to give the title compound (1.71 g, 99%). 1H NMR (300 MHz, CDCl3): δ ppm 0.87 (m, 3 H) 1.24 (m, 4 H) 1.57 (m, 3 H) 1.98 (m, 2 H) 7.32 (m, 5 H). MS (DCI NH3+) m/z 224 (M+NH4)+.

Provenance & Evidence