Sodium Hydroxide → HCID 68873352, compound

Participants

Reaction Steps

A suspension of the product of Example 43H in water (3 mL) was treated with 0.997N sodium hydroxide solution (0.204 mL) and stirred at 250C for 1 hour. The solution was lyophilized to give 112 mg (84%) of a yellow solid. 1H NMR (300 MHz, DMSO-d6): δ ppm 0.49 m, 1 H) 0.66 m, 6 H) 0.92 m, 2 H) 1.11 m, 2 H) 1.38 (s, 3 H) 1.72 (m, 1 H) 2.14 (m, 1 H) 2.96 (s, 3 H) 7.33 m, 3 H) 7.45 m, 3 H) 8.05 (d, J=7.72 Hz, 1 H) 9.88 (s, 1 H) 15.50 (s, 1 H); MS (ESI−) m/z 530 (M−H)−.

Provenance & Evidence