HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2224953Generated: November 1, 2026
Dimethylformamide → 2-(4-Methoxyphenyl)-2,5-dimethylhexanoyl chloride
https://huagongshe.com/reaction/2224953
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | HCID 68870239 | HCID 68870239 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2-(4-Methoxyphenyl)-2,5-dimethylhexanoyl chloride | HCID 87608862 | — |
Reaction Steps
To a cooled solution of Example 155C (8.52 g, 0.034 mol) in 200 mL anhydrous dichloromethane was added 2 N oxalyl chloride in dichloromethane (26 mL, 0.052 mol) and drops of dimethylforamide. The solution was stirred for 30 minutes at 0° C. and then room temperature for 2 hours. The solvent was removed under vacuum and the crude product used directly.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07378414B2 |
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| Source dataset | uspto-grants-2008_05 |
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| ORD ID | ord-d8f7efb797754060abba6d16b8a3bf53 |
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| Source note | uspto-grants-2008_05 |
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