HCID 68871456, compound → HCID 68870978, compound

HRID 2224973Notes

Reaction equation

HRID 2224973 reaction equation
[OH:1][CH2:2][CH2:3][N:4]([CH3:24])[C:5]([C:7]1([CH2:19][CH2:20][CH:21]([CH3:23])[CH3:22])[C:16]2[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=2)[CH2:10][CH:9]=[C:8]1[O:17][CH3:18])=[O:6].C[O:26][C:27]1[C@](C(N2CCC[C@@H]2CO)=O)(CCC(C)C)C2C(C[CH:36]=1)=CC=CC=2>>[C:27]([O:1][CH2:2][CH2:3][N:4]([C:5]([C:7]1([CH2:19][CH2:20][CH:21]([CH3:22])[CH3:23])[C:16]2[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=2)[CH2:10][CH:9]=[C:8]1[O:17][CH3:18])=[O:6])[CH3:24])(=[O:26])[CH3:36]

Participants

3

Reactant 2

HCID 68871456HCID 68871456, compoundHCID 68874183HCID 68874183, compound

Product 1

HCID 68870978HCID 68870978, compound

Procedure

The title compound was prepared using the procedure described for Example 171C, substituting the product from Example 176B for the product from Example 171B. The title compound was purified by column chromatography on silica gel using a solvent gradient of 35-65% ethyl acetate in hexane, and was obtained as a colorless solid.

Workup

  1. customThe title compound was purified by column chromatography on silica gel using a solvent gradient of 35-65% ethyl acetate in hexane
  2. customwas obtained as a colorless solid

Sources & evidence

ORD record
ord-02db5391b4d9416288a8dc1bd5191fef
Source dataset
uspto-grants-2008_05
Patent number
US07378414B2

Reaction notes

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