反应详情

5-Methoxycarbonyl-2-furyl phenyl ketone (5.5 g, 0.024 mole) was dissolved in methanol (60 ml), added with benzylhydrazine (9 g, 0.07 mole) and acetic acid (0.5 ml) and then heated under reflux till the reaction was completed. After cooling, the solvent was evaporated. The resultant residue was extracted with chloroform and washed with dilute HCl solution, then water, and then dried over anhydrous magnesium sulfate and filtered. The solvent of the filtrate was removed to give 5-methoxycarbonylfuryl phenyl ketone benzylhydrazone.

1. temperatureheated
2. temperatureunder reflux till the reaction
3. temperatureAfter cooling
4. customthe solvent was evaporated
5. extractionThe resultant residue was extracted with chloroform
6. washwashed with dilute HCl solution
7. dry with materialwater, and then dried over anhydrous magnesium sulfate
8. filtrationfiltered
9. customThe solvent of the filtrate was removed