Succinic anhydride → HCID 11464123, compound

HRID 2225020Notes

Reaction equation

[CH2:1]([N:8]1[C:16]2[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=2)[C:10]([C:17]2[CH:22]=[CH:21][C:20]([CH2:23][OH:24])=[CH:19][CH:18]=2)=[N:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:25]1(=[O:31])[O:30][C:28](=[O:29])[CH2:27][CH2:26]1>>[CH2:1]([N:8]1[C:16]2[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=2)[C:10]([C:17]2[CH:18]=[CH:19][C:20]([CH2:23][O:24][C:25](=[O:31])[CH2:26][CH2:27][C:28]([OH:30])=[O:29])=[CH:21][CH:22]=2)=[N:9]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

Reactant 2

HCID 7922Succinic anhydride

HCID 10892401HCID 10892401, compound

Product 1

HCID 11464123HCID 11464123, compoundYield 75%

Procedure

1-Benzyl-3-(4′-hydroxymethylphenyl)indazole was reacted with succinic anhydride according the procedure described in Example 1 (d) to afford Compound 9 in a yield of 75%.

Sources & evidence

ORD record: ord-72c4423e602244268cae8e5fa2e2b337
Source dataset: uspto-grants-2008_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07378532B2

Reaction notes

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