HCID 69286135, compound → HCID 69284649, compound

Participants

Reaction Steps

A solution of benzyl 2-((1S,2S,4R)-2-isopropyl-4-(isopropyl(methyl)amino)cyclohexylamino)-2-oxoethylcarbamate trifluoroacetate (188 mg) in MeOH (10 mL) was charged with 10% Pd/C, Degussa (30 mg). The reaction flask was evacuated and then back-filled with hydrogen; this was repeated three more times. The reaction was stirred under 1 atm of H2 for 3 h and then filtered and concentrated to afford 2-amino-N-((1S,2S,4R)-2-isopropyl-4-(isopropyl(methyl)amino)cyclohexyl)acetamide (120 mg). MS found: (M+H)+=270.3.

Provenance & Evidence