Hydrochloric Acid → HCID 86596959, compound

Participants

Reaction Steps

A solution of tert-butyl(1R,3R,4S)-4-benzyloxycarbonylamino-3-(isopropylsulfonylmethyl)cyclohexylcarbamate (111 mg) in ethyl acetate (4 mL) was treated with a solution of HCl in dioxane (4.0 M, 4 mL). The mixture was stirred at rt for 50 min, then was concentrated to provide the hydrochloride salt of benzyl (1S,2R,4R)-4-amino-2-(isopropylsulfonylmethyl)cyclohexylcarbamate (100 mg) as a white glassy solid. MS found: (M+H)+=369.2.

Provenance & Evidence