HCID 69286629, compound → HCID 86596970, compound

Participants

Reaction Steps

Tert-butyl (1R,3R,4S)-3-acetyl-4-benzyloxycarbonylaminocyclohexylcarbamate (600 mg) in MeOH (5 mL) was charged with 5% Pd/BaSO4 (300 mg). The reaction flask was evacuated and then back-filled with hydrogen; this was repeated three more times. The reaction was stirred under 1 atm of H2 for 2 h and then filtered and concentrated to provide tert-butyl (1R,3R,4S)-3-acetyl-4-aminocyclohexylcarbamate (430 mg). MS (ES+)=279.2 (M+H)+.

Provenance & Evidence